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This study suggests that executive functions are a key area vulnerable in early-stage PD with mild cognitive impairment (PD-MCI) and can be improved through a KD

However, despite their health benefits, the low absorption rate of polyphenols (approximately 510% via the small intestine) and their rapid metabolism and excretion significantly limit their ability to reach target tissues (114)

The nine tissue systems now documented in the preclinical literature were not predicted by computational models or receptor-binding assays at the outset they were identified sequentially as researchers in different laboratories independently tested the compound against different experimental injury models and consistently found meaningful effects

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