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They work, but their origin raises real questions around immunological safety, sterility, ethical sourcing, and regulatory oversight, and they tend to be less stable

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GLP-1 receptor agoniststhe class of drugs that includes semaglutide (Ozempic, Wegovy), liraglutide (Victoza, Saxenda), and tirzepatide (Mounjaro, Zepbound)are synthetic molecules engineered to mimic and amplify this exact hormonal signal

One of the pathways responsible for endothelial dysfunction associated with diabetes is the binding of oxidized low-density lipoprotein (ox-LDL) to its endothelial receptor, lectin-like ox-LDL receptor 1 (LOX-1)