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In particular we have outlined the importance of synaptic copper regulation by A species, the importance of Tau in neuronal MT and nucleus stability and the lipid modulation of ApoE under physiological conditions, and how all of these can perform additional functions as AMPs which can be best described as protein or peptide moonlighting (Espinosa-Cant et al., 2020)

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The Mechanism of Dual Receptor Agonism The survodutide mechanism can be split into two complementary limbs that map onto its two receptor targets

The choice of administration route often depends on the intended therapeutic target and whether localized or systemic effects are desired