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Mass spectra were measured in linear positive mode, using an AutoflexSpeed MALDI mass spectrometer (Bruker Daltonics)

doi: 10.1016/j.intimp.2023.111168 93 ZouYYuXZhouCZhuCYuanY

Shift Toward Lighter Pigment Shift Toward Lighter Pigment Some studies suggest glutathione may promote the formation of pheomelanin , a lighter pigment, rather than eumelanin , which produces darker tones

Hyperoside has been demonstrated to ameliorate depressive-like behavior by promoting M2 polarization of microglia in the hippocampus (266), and quercetin can alleviate cognitive impairments in depressed mice by targeting HSP90 to inhibit the activation of the NLRP3 inflammasome in microglia (267)