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Many people begin to notice a brighter, more "rested" look in their skin within 4 to 8 weeks of consistent use, while more significant changes in skin tone may take 3 to 6 months

[2] [7] These effects typically diminish over time but can be pronounced during the initial weeks of treatment or following dose increases

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Similarly, reusing needles or syringeseven on the same vial for the same patientsignificantly increases infection risk and can introduce particulate matter or dulled needles that damage the rubber stopper, creating a pathway for contamination