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Often they are described as non-lethal agents, but if administered in high enough doses, incapacitating agents can results in death or serious morbidity

Wong TL, Che N, Ma S (2017) Reprogramming of central carbon metabolism in cancer stem cells

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demonstrated that, under physiological conditions, macrophages could, uptake native Hb without the binding protein Hp through CD163 (Schaer et al., 2006)