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Important in this context is the recent development of drug, a small TAT-TrkB peptide, that prevented TrkB-FL cleavage, improved cognitive performance, ameliorated synaptic plasticity deficits and prevented Tau pathology progression in vivo in a mouse model of AD [233]

Proteomics and metabolomics approaches could be used to identify specific oxidative modifications in sperm proteins and metabolites, providing more detailed insights into the molecular mechanisms of oxidative stress-induced sperm damage

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis