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Acute symptoms such as fatigue may improve relatively quickly, whereas neurological symptoms like paraesthesia (pins and needles) or cognitive difficulties typically require longer treatment courses

Phase Weeks 3+ (higher end) Daily dose 150 mg once daily Notes Some sources go this high

This selective fat loss improves body composition without sacrificing lean muscle mass, a critical advantage over many weight loss interventions that result in both fat and muscle loss

These sequences were then run through an R script (Supplementary Materials, bash_DADA2 + IDTAXA_workflow_Illumina-PairedEnd_V1V3.R) which trimmed reverse reads to 260 bp, removed forward reads exceeding a maximum expected error of three, and truncated reverse reads exceeding a maximum expected error of six