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The selective inhibitor compound 27 (IPN60090), which is currently in a first-in-class clinical trial, focuses on optimising physicochemical and pharmacokinetic properties, with a strong in vivo target engagement capability, and should strongly inhibit GLS in humans [152, 153]

And the term "copper peptides" itself is doing a lot of unearned work, because it lumps together GHK-Cu (the molecule with 50 years of evidence) with AHK-Cu, GHK-NH2, and a range of synthetic copper-binding sequences that have far thinner mechanism data

Petrocelli, J

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