At a molecular weight of approximately 340 Da as the free tripeptide (see the GHK-Cu compound overview), it sits below the 500 Da threshold commonly associated with good dermal penetration a key reason GHK-Cu topical serum formulations achieve dermal absorption where many larger cosmetic peptides do not
Semin Cancer Biol 50:112 Borkhardt A, Repp R, Haas OA, Leis T, Harbott J, Kreuder J, Hammermann J, Henn T, Lampert F (1997) Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23)
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Q: When can patients expect to see improvement after administration