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Storing the reconstituted vial at room temperature
Interestingly, one of the mechanisms that causes POTS is a disturbance in the renin-angiotensin system, possibly due to inadequate ACE2 activity, which is one of the receptors used by the SARS-CoV-2 virus in causing Covid.[ref][ref][ref] POTS is a common autonomic disorder following Covid and in long Covid.[ref][ref] Some researchers point to SARS-CoV-2 invading the central nervous system in POTS, while others point to the changes in endothelial function
"Elevated serum homocysteine, low serum vitamin B12, folate, and age-related macular degeneration: the Blue Mountains Eye Study"
Treatment is often initiated at a high dose, followed by a maintenance dose given less frequently, as determined by the patient's B12 levels and clinical response
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