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In one embodiment, when one or more buffers are utilized in the formulations of the present disclosure, they are combined, e.g., with a pharmaceutically acceptable vehicle and are present in the final formulation, e.g., in an amount ranging from about 0.1% to about 20%, from about 0.5% to about 10%

At the concentrations used in standard research protocols this is not expected to be a practical issue, but it is a relevant consideration when designing chronic dosing studies

Research Profile Investigated in cell culture studies for interactions with collagen and glycosaminoglycan synthesis Subject of preclinical wound model research examining fibroblast activity Studied in vitro for superoxide dismutase and antioxidant enzyme interactions Not approved for human use For in vitro research and laboratory use only

Researchers seeking to evaluate PTD-DBM as an isolated variable may prefer single-ingredient formulations