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Unlike signal peptides (e.g., palmitoyl pentapeptide-4) that primarily stimulate collagen synthesis, or carrier peptides (e.g., manganese tripeptide-1) that facilitate mineral transport, GHK-Cu functions as a copper transporter with direct antimicrobial activity

A 2024 study (PMID: 39902373) developed a food-derived tripeptide-copper self-healing hydrogel incorporating GHK-Cu for infected wound healing research, demonstrating the compounds compatibility with advanced drug delivery platforms

Biomechanics Anastomosis dehiscence was biomechanically assessed in separate groups of animals, under deep anesthesia as described before (35, 42, 43)

It modulates expression of thousands of genes involved in tissue remodeling and signaling