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1 H-NMR analysis 1 H-NMR analysis of serum samples was conducted using a Varian UNITY INOVA 500 spectrometer operating at 499.839 MHz for proton and equipped with a 5 mm double resonance probe (Agilent Technologies, CA, USA)

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Transduced DG-75 cells (2 10 6 ) in 0.1 ml of phosphate buffer saline (PBS) were injected subcutaneously in the dorsal flanks of 8-to 10-week-old female NOD.CB17-Prkdcscid/J mice (Charles River Laboratories, Wilmington, MA, USA)

Similarly, HCl was added to DDW control cultures until the pH reached the levels of 5OP treated cultures