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Diffraction images of 0.03 or 0.05 rotation were recorded on either a Pilatus3 6M, or Eiger2 X 16M detector (see Table 1) using a beam size of 80(H) 20(V) m 2

The NOD-like receptor family pyrin domain containing 3 (NLRP3) comprises a large molecular weight protein assembly, incorporating NLRP3, ASC, and caspase-1, which forms an inflammatory vesicle

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