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Resources Centers for Disease Control and Prevention, National Center for Health Statistics

The results demonstrated that untreated BMDMs responded strongly to proinflammatory stimuli, as evidenced by increased intracellular ROS generation, elevated expression of the M1 biomarker CD86, and higher release of pro-inflammatory cytokines (TNF- and IL-6)

10.1016/J.FREERADBIOMED.2024.12.053 131

and because the ROS are chemically bound to the glutathione molecule, they cant react with cellular machinery to impair their function and cause damage.* Glutathione is thus said to be an antioxidant.* In addition to its potent antioxidant activity, glutathione also supports the other cellular antioxidant systems in the body by offloading excess ROS from them and allowing them to be metabolized safely.* The Complex Relationship Between Glutathione and the Thyroid Glutathiones relationship with the functioning of the thyroid gland is indirect