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Research suggests that intramuscular delivery achieves significantly higher plasma concentrations than oral supplementation, making injectable Vitamin C a clinically effective option for patients with deficiency, compromised immune function, or chronic fatigue

These changes were characterized by either an increase in muscle size and density or a reduction in fat content

Data availability The dataset supporting the conclusions of this article is available in the SRA repository [ information is available in the Additional files 1 to 4

Increased expression of VEGF stimulates angiogenesis, acting on dopamine D1 receptors, and may cause, among other things, dyskinesia, a major side effect of L-DOPA, which may further reduce the quality of life of PD patients under L-DOPA medication (Veith and Henderson 2019) Increased VEGF expression has been also documented in astrocytes, endothelial cells (ECs), and monocytes of MS patients, potentially contributing to BBB permeability and the onset of MS