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Studies reveal enhanced fatty acid oxidation, increased energy expenditure, and improved metabolic efficiency through direct NNMT inhibition, positioning it as breakthrough tool for investigating obesity mechanisms without appetite suppression

This reduced activity, combined with a potentially slower metabolism that can occur with persistent nutrient deficiencies, could indirectly contribute to weight gain over time

Drug Interactions: Semaglutide may interact with other medications, potentially affecting their effectiveness or increasing side effects

If the safety and modest efficacy data from the published trials translate to our patient population, it would give us a tool that acts directly on fat cell metabolism rather than appetite, with a side effect profile that appears extremely well-tolerated