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Hudson M, Baron M, Colmegna I, Bernatsky S, Klein Oros K, Pastinen T, Greenwood C

Currently, EGFR, epithelial cell adhesion molecule (EpCAM), VEGFR-2, and programed death-1 (PD-1) have been selected for development of MET-based bispecific TMABs

Approval was based on data from the KEYNOTE-671 trial, where Keytruda plus chemotherapy showed an advantage over placebo plus chemo in both overall survival and investigator-assessed event-free survival

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