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Increased expression of VEGF in the brain has been associated with cerebral ischemia, increased BBB permeability and pathological vascular remodeling, which may contribute to the progression of neurodegenerative diseases

The study further examined the impact of Goralatide on the proliferative activity of normal, remission, and leukemic progenitor cells, illustrating that under control conditions, erythroid progenitor cells are highly proliferative, with 38% of CFU-E and 30% of BFU-E cells in the S-phase of the cell cycle