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Reprod Biomed Online 39(6):893904

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Although the mechanism underlying the augmented excitatory neuronal tone in autism is yet to be clarified, several lines of evidence support that astrocytes are involved in the modulation of the neuronal excitability in central nervous system diseases 21,22 , as astrocytes are involved in the regulation of Glu, Gln, and GABA levels in the brain 23