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For confounding to occur, the extraneous factor must be associated with both the primary exposure of interest and the disease outcome of interest

Secondary cigar smokers, however, have learned to inhale smoke, and increase their risk of cancer and heart disease

People who used to smoke but switched completely to e-cigarettes improved their respiratory symptoms (Goniewicz et al., 2020), including people with chronic obstructive pulmonary disease (COPD

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