158(7):23092318 Sun GW, Kobayashi H, Suzuki M, Kanayama N, Terao T (2003) Follicle-stimulating hormone and insulin-like growth factor I synergistically induce up-regulation of cartilage link protein (Crtl1) via activation of phosphatidylinositol-dependent kinase/Akt in rat granulosa cells
J Clin Endocrinol Metab 93(4):13391344 Bertram L, Tanzi RE (2008) Thirty years of Alzheimers disease genetics: the implications of systematic meta-analyses
The accumulation of visceral fat, a typical symptom of obesity, leads to the production of adipokines such as leptin (8), lipocalin (9), C1q tumor necrosis factor-related protein 9 (10), chemerin (11), and retinol-binding protein 4 (12), which are involved in a variety of metabolic processes such as glucose uptake, insulin signaling, and fatty acid oxidation, and are highly correlated with T2DM and cardiovascular and microvascular complications are highly relevant (13, 14)
Take a digestive organ cell, for example, we'll assume that it requires high amounts of NADPH for fatty acid synthesis
