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Although the effect in islets is milder, we believe it mimics the clinical scenario observed in human carriers of Taz loss-of-function mutations, who show mild or no endocrine symptoms, while still recapitulating the cardiac dysfunction characteristic of BTHS

Puchalska, P

Ramucirumab versus placebo in combination with second-line FOLFIRI in patients with metastatic colorectal carcinoma that progressed during or after first-line therapy with bevacizumab, oxaliplatin, and a fluoropyrimidine (RAISE): a randomised, double-blind, multicentre, phase 3 study

This synergy of bioactive peptides and Silybum marianum (silybin) marks a new era of multi-mechanistic, clinically validated skin rejuvenation