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Here are the signs you need to look out for: Neck and back pain Numbness, weakness, cramping, or pain in the arms or legs Pain going down the leg Foot problems While the above symptoms are can help determine whether a patient has spinal stenosis, one type of the disease, called cauda equina syndrome, is very serious

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It is now widely accepted that oxidative stress can lead to changes in the expression of specific genes including renal injury-related genes, like kidney injury molecule 1 (KIM-1), tumor necrosis factor alpha (TNF-), and Neutrophil gelatinase-associated lipocalin protein (NGAL) [15]

an event characterized by loss of cell membrane asymmetry, cell shrinkage, and an increase in intracellular Ca 2+ , primarily due to dysregulated Ca 2+ influx [436]