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These topics are useful for understanding why the compound appears in biological research, while still requiring careful interpretation of evidence type and study context

George A, Pushkaran S, Li L, An X, Zheng Y, Mohandas N, et al

Resveratrol administration after prenatal exposure to VPA in rats, resulted in prevention or reduction of autism-like social deficits, pregnant Wistar females received a single intraperitoneal dose of VPA (600 mg/kg) on gestational day 12, while resveratrol was administered subcutaneously at 3.6 mg/kg/day from gestational day 6.518.5

Important gaps in understanding that could accelerate the clinical translatability of CNS genetic interventions are addressed, and we present lessons learned from failed clinical trials that may guide the future development of gene therapies for the treatment and management of CNS disorders