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doi: 10.1038/s41598-024-71731-6 50 LiuJHChenCYLiuZZLuoZWRaoSSJinLet al

Studies of lipopolysaccharide effects on the induction of -synuclein pathology by exogenous fibrils in transgenic mice

Different hypotheses have been brought forward to explain the evolving LB pathology across the brain, including: retrograde transport of pathological -synuclein via neuroanatomical networks, -synucleins prion-like behavior, and cell- or region-autonomous factors 2,3