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The functional neuroanatomy of tinnitus: evidence for limbic system links and neural plasticity

Rotem A, Janzer A, Izar B, Ji Z, Doench JG, Garraway LA, et al

Although the time course of Nrf2 stabilization and nuclear translocation indicated a rapid increase with a peak at approximately 6 h for DEM, and a slow but gradual rise triggered by NFT, maximal accumulation of Nrf2 protein, as well as the induction of GCLC and glutathione synthesis, were almost identical for both NFT and DEM after incubation periods of and beyond 24 h (Fig

This ensures maximum absorption and bioavailability, ultimately increasing its antioxidant benefits