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MDA level evaluation To evaluate the concentration of malondialdehyde (MDA), the supernatant obtained from Liver homogenate was treated with 2 mL of thiobarbituric acid (TBA) and subjected to heating at 100 C for a duration of 15 min

Phthalates Phthalates are anti-androgenic and estrogenic EDCs that can be found in plastics, medical devices, and childrens toys

This finding is consistent with the increasingly appreciated consensus that bypass or inactivating ferroptosis is a hallmark mechanism co-opted by oncogenic KRAS mutations to overcome the oxidative barrier during tumor development, progression, and metastasis [40-42, 61, 62]

STAT3 signaling controls cellular senescence and immunosenescence There is clear evidence that insulin/IGF-1 exposure can induce/augment the cellular senescence of different non-immune cells in several experimental conditions [144,145,146,147]