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Centrally, there was intracranial (superior sagittal sinus) hypertension, brain swelling and severe lesions [14,15,16,17,18,19,20]

TDP6 represents a next-generation approach to peptide-based remyelination, designed from the ground up to target the specific receptor that drives oligodendrocyte maturation and myelin production

The pathological changes could also include altered brain metabolism, excitotoxicity, free radical generation, neuroinflammation, blood-brain barrier dysfunction, and apoptosis

Standalone or combinatorial regimens designed around potent bio-absorptive reductants, elevating the efficiency of palliative treatment by decreasing or delaying disease progression, will be a welcome step for further trials and those affected by the disease