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Bombesins are synthesized by both the nervous system [192] and by pulmonary neuroendocrine cells [193], as well as other tissues [194]

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VEGF represents one of the major regulators of the interaction between myeloid cells and endothelial cells in cancer (4446, 81), but is also involved in the crosstalk with NK cells (108111), and the interaction between ILC and tumor endothelial cells is regulated by TNF, IL-8 and TGF- (114, 124) ( Figure 3 )

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