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N -methyl putrescine then undergoes deamination into 4-methylaminobutanal by the N -methyl putrescine oxidase (MPO) enzyme, 4-methylaminobutanal then spontaneously cyclize into N -methyl- 1 -pyrrollidium cation

Mostly it doesnt trigger a positive result

Nova Scotia (NS) : $19$21 per pack New Brunswick (NB) : $18$19 per pack Prince Edward Island (PEI) : $19$20 per pack Newfoundland & Labrador (NL) : $21$23 per pack Newfoundland & Labrador holds the highest cigarette prices in Canada, driven by aggressive provincial taxation

Reported exposure to e-cigarette advertising for each media type by e-cigarette user status for the aggregated sample is shown in Table 1, and results for individual countries are reported in Supplementary file Tables 25