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USA 87 , 13421346 (1990)

The levels of serum inflammatory cytokines and other measurements were carried out

Furthermore, peripheral insulin resistance triggered by uremia, metabolic acidosis and low-grade inflammation is common in CKD (80), leading to intra-portal hyperinsulinemia, but does not necessarily increase hepatic sensitivity to GH because of the reduced hepatic expression of IGF-I and GHR mRNA (81)