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While the 28-day treatment period and use of only male rats were consistent with standard protocols to reduce variability in early-phase toxicological studies, these choices limit the extrapolation of our findings to chronic exposure scenarios and across sexes

A study published in The New England Journal of Medicine showed that male participants over 60 years old, who took hGH for six months gained on average 8.8% lean body mass and lost 14% fat mass

Of note, only with the BPC 157 application was a beneficial outcome observed, i.e

ViiV backed the supplemental application with data from the DANCE study, which evaluated Dovato in treatment-naive adolescents, along with evidence from well-controlled studies in adults