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A snug fit is essential to prevent the tube from splitting during the injection process

In July 1949 issues of both local and national medical journals, RJ Reynolds asked, How mild can a cigarette be? In answering this question, the advertisement juxtaposed a doctors reportillustrated with a physician, cigarette in hand and head mirror strapped around his browwith a smokers reportillustrated with a smiling Sylvia MacNeill, secretary. Physicians, the advertisement explained, had concluded after scientific investigation that there was not one single case of throat irritation from smoking Camel cigarettes

Nicotine Tob Res 2004;6:7984