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What Tesamorelin Does: Increases endogenous growth hormone Reduces visceral adipose tissue (VAT) Improves waist circumference Supports IGF-1 balance May improve liver fat markers Tesamorelin has been studied extensively in HIV-associated lipodystrophy, where it significantly reduced visceral fat without the same degree of subcutaneous fat loss

5.1.3 Modulating immune and inflammatory pathways Targeting key regulators such as NF-KB and Nrf2 can not only reduce proinflammatory cytokine production but also indirectly rebalance iron homeostasis

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