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Although critical glutathione levels will lower as we age, depletion can be accelerated by stress, illness, infection, poor diet, alcohol, cigarettes, trauma, and environmental toxins

Next to assess Dihexas metabolic stability in the liver, pooled male rat liver microsomes were used

First, current biomarkers (such as serum GPX4) are derived from mouse controlled cortical impact (CCI) models, yet the pathological heterogeneity of human TBI far exceeds that of animal models, making these biomarkers inadequate for guiding clinical treatment

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