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Further monitoring of the cancer cells for an additional 10 h demonstrated the gradual decrease of the red fluorescence signal, indicative of the degradation of the nanoparticles inside the cancer cells (Supplementary Fig

Systematic site rotation also reduces the risk of localised lipodystrophy (changes in fat distribution) and the development of persistent lumps or subcutaneous nodules at frequently used injection points

Szatkiewicz JP, ODushlaine C, Chen G, Chambert K, Moran JL, Neale BM, et al

Local reactions may include erythema, pruritus, induration, or mild pain at the injection site, potentially affecting five to ten percent of patients