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The consensus is that GHK-Cu is safe compared to its alternatives

Notably, the various botanical products have product-specific chemical fingerprints (qualitative and quantitative compositions) corresponding to various pharmacological profiles (conditional signatures) derived from the same medicinal plant and different characteristics of quality (based on product specifications), efficacy, and safety [69]

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considering the brain and the CNS specifically, BBB penetration rates and the P-glycoprotein (P-gp) efflux pump are critical factors limiting their application in the clinic [1]