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Spectrochim Acta A Mol Biomol Spectrosc

Schisandrol A from Schisandra chinensis reverses p-glycoprotein-mediated multidrug resistance by affecting Pgp-substrate complexes

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Nasal spray considerations: Typically lower bioavailability than injection, requiring somewhat higher doses Faster onset in some users due to direct CNS access More convenient and less intimidating for needle-averse individuals Requires properly calibrated spray bottles for accurate dosing Converting from injectable to nasal dosing is not straightforward