Exposure to temperatures above 86F (30C) can cause the active ingredient in Wegovy, semaglutide, to break down and you must discard the pen when exposed to extreme temperatures or direct sunlight
In a randomized, placebo-controlled intervention study with more than 900 older participants experiencing psychological distress, daily supplementation with folic acid (400 g) and vitamin B 12 (100 g) for two years did not reduce the occurrence of symptoms of depression despite significantly improving blood folate, vitamin B 12 , and homocysteine levels compared to placebo (109)
B12 Side Effects in Elderly: Safety Guide for Older Adults Vitamin B12 supplementation is commonly prescribed for elderly patients, as deficiency becomes increasingly prevalent with age due to reduced gastric acid production, pernicious anaemia, and medication interactions
Although other sources also refer to higher levels of vitamin B6 for helping Raynauds Phenomenon 6 , the InfantRisk Centre urges caution stating that vitamin B6 has been associated with seizures at doses of 300 mg/day or more and doses above 600 mg/day could decrease a mothers milk supply 7