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Cell Microbiol (2005) 7(12):170713

The effect of exercise training on resting concentrations of peripheral Brain-Derived Neurotrophic Factor (BDNF): a meta-analysis

Cardiovascular and Neurological Effects Cardiovascular research has revealed protective effects against various cardiac injuries, with studies showing benefits in arrhythmia models, protection against potassium-induced cardiac damage, and improved recovery from ischemia-reperfusion injury

Alternative Routes of Administration & the First-Pass Effect There are several reasons for different routes of administration used in clinical medicine ( Table 33 )for convenience (eg, oral), to maximize concentration at the site of action and minimize it elsewhere (eg, topical), to prolong the duration of drug absorption (eg, transdermal), or to avoid the first-pass effect (sublingual or rectal)