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Activation of GPR30 using the selective agonist G-1 has been shown to promote hair growth in C57BL/6J mouse skin by upregulating Wnt and Hedgehog signaling pathways [140]

Methods 103:175179

And weight gain is often driven by multiple factors: hormones, insulin resistance, medications, sleep deprivation, stress, and muscle loss

81800666 to B.L.), the Guangdong Basic and Applied Basic Research Foundation (2021A1515111199 to J.C.), the Natural Science Foundation of Guangdong Province (2023A1515010422 and 2025A1515012781 to B.L