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A 2005 study published in the European Journal of Endocrinology characterized ipamorelin's pharmacokinetics in healthy volunteers and found a plasma half-life of approximately 2 hours with rapid peptidase-mediated clearance (Raun et al., 2005) [5]

DOI: 10.1172/JCI5461

One of the primary mechanisms by which HRT improves cognitive function is by restoring estrogen levels in the brain, thereby promoting neurogenesis and synaptic plasticity