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Concurrently, SCFAs reduce iron absorption by inhibiting HIF-2 and upregulate ferritin expression to lower the labile iron pool, thus attenuating Fenton reaction-mediated lipid peroxidation (51)

Furthermore, the included studies were heterogeneous concerning the characteristics of patients and study design (2 of studies on L-carnitine supplementation have been performed in the setting of hemodialysis when carnitine metabolism is altered in uremia and the depletion of carnitine is expected 62 , 4 in diabetic/metabolic syndrome patients with dyslipidemia and 1 in hyperlipidemic patients)

Compounding pharmacies involved in the preparation of synthetic peptides must adhere to stringent protocols to safeguard the integrity of these research materials