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Based on the current literature, however, it is clear that more research is necessary to uncover the specific beneficial mechanisms behind the anti-inflammatory properties of selenoproteins and other Se metabolites, especially as related to eicosanoid biosynthesis

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In addition, CHE is reported to bind to non-telomeric G-quadruplex sequences also in the promoters of other genes, which binds to G-quadruplexes at promoters of VEGFA, BCL2, and KRAS genes and downregulates their expression (Jana et al., 2017)

Studies show that low selenium leads to abnormal sperm morphology, especially in the head and midpiece regions [13]