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25 In a controlled trial in 41 patients with sudden sensorineural hearing loss, those who received NAC along with intratympanic (through the eardrum) injections of the steroid dexamethasone for 14 days gained an ability to hear a specific high pitch (8,000 Hz) and were more likely to recover their hearing than those who received intratympanic steroid injections alone

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From these observations we can conclude that the MGST1 GSH binding site appears to be rather malleable

It does not follow that every higher exposure buys a meaningful clinical benefit