Injectable NAD+ delivers the coenzyme directly into the bloodstream, bypassing the digestive system for more efficient absorption compared to oral forms or supplements
Possible adverse effects may include: Injection site reactions : Redness, swelling, irritation, or discomfort Gastrointestinal symptoms : Nausea, vomiting, stomach cramps, or diarrhea Headaches or dizziness Allergic reactions : Rash, itching, shortness of breath, or facial swelling (rare) Increased heart rate or anxiety (typically temporary from B-vitamins) Fatigue or weakness if used improperly Elevated liver enzymes when taken in excess particularly with methionine or choline Insomnia if taken late in the day due to increased energy levels Who should avoid or use caution
The panel agreed that initial treatment should be parenteral for severe cases, while high-dose oral B12 can be considered for maintenance
Clinical safety data from phase II trials for inflammatory bowel disease show BPC-157 exhibited particular wound healing effects with no reported toxicity