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They serve as messengers in the body, stimulating important biological processes such as: Fat burning Muscle repair Hormone regulation Appetite control Skin rejuvenation Enhanced immunity Cellular longevity As you age, your natural peptide levels decline, leading to slower metabolism, weight gain, fatigue, and reduced recovery

However, given that appendages occupy only 0.1% of the total skin surface, they account for a deficient proportion of the total transport of compounds through the skin [22,23]

Strengthens immune system

Ethics statement The animal study was reviewed and approved by the Ministry of the Environment and the Agency for Cultural Affairs in Japan and the Animal Research Committee of Iwate University