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However, it can take decades of follow-up and complex study designs for such increased risk to show up in the data

4,11 ASK the patient about all types of tobacco and nicotine being used at every visit, choosing the statement that best describes their tobacco or nicotine use, thereby reducing underreporting from asking yes or no questions 4 : I have never used tobacco or nicotine or have used minimal amounts of tobacco or nicotine in my lifetime (for example, fewer than 100 cigarettes in my lifetime)

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